New synthesis of cycloalca[с]nicotinoamide and nitrile derivatives

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Resumo

Nitriles and amide of nicotinic acid were synthesized by Knoevenagel reactions, nucleophilic vinyl substitution (SNVin), and alkylation. The structure of (1-amino-5-phenyl-5,6,7,8-tetrahydrothieno[2,3- c ]isoquinolin-2-yl)(phenyl)methanone was studied by X-ray analysis.

Sobre autores

I. Dyachenko

Lugansk State Pedagogical University

V. Dyachenko

Lugansk State Pedagogical University

P. Dorovatovskii

National Research Center “Kurchatov Institute”

V. Khrustalev

Peoples’ Friendship University of Russia (RUDN University);Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

G. Abakarov

Dagestan State Technical University

V. Nenajdenko

Lomonosov Moscow State University

Email: nenajdenko@gmail.com

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