Electroconductive Materials Based on Polylactide and Polypyrrole for Biomedical Applications

N. A. Zavrazhnykh; Завражных Н. А.; I. Yu. Sapurina; Сапурина И. Ю.; M. A. Shishov; Шишов М. А.; E. M. Ivan’kova; Иванькова Е. М.; V. P. Orlov; Орлов В. П.; V. E. Yudin; Юдин В. Е.

doi:10.31857/S2308112023700529

Electroconductive Materials Based on Polylactide and Polypyrrole for Biomedical Applications

作者: Zavrazhnykh N.A.¹, Sapurina I.Y.², Shishov M.A.²^,1, Ivan’kova E.M.²^,1, Orlov V.P.³, Yudin V.E.²^,1
隶属关系:
1. Peter the Great St. Petersburg Polytechnic University
2. Institute of Macromolecular Compounds, Russian Academy of Sciences
3. Kirov Military Medical Academy, Ministry of Defense of the Russian Federation
期: 卷 65, 编号 3 (2023)
页面: 194-204
栏目: МЕДИЦИНСКИЕ ПОЛИМЕРЫ
URL: https://permmedjournal.ru/2308-1120/article/view/650825
DOI: https://doi.org/10.31857/S2308112023700529
EDN: https://elibrary.ru/MKYSNZ
ID: 650825

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详细

Electroconductive scaffolds of different shape for tissue engineering have been obtained on the basis of two biocompatible polymers: polylactide and polypyrrole. The composite scaffolds have been based on porous permeable films or tubes of polylactides prepared via electrospinning. A layer of electroconductive polypyrrole has been applied at the developed surface of the scaffolds consisting of the chaotically interwoven fibers of micron-scale thickness. The structure of the tissue engineering scaffolds as well as their mechanical, redox, and electroconductive properties have been investigated. It has been found that the scaffolds are stable during electrical stimulation via prolonged application of the cyclic potentials.

参考

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