The role of pathological stress increase in blood pressure as a risk factor for hypertensive remodeling of the left ventricle in young people with different baseline blood pressure levels

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Abstract


Objective: To assess the role of pathological stress increase of blood pressure as a risk factor for hypertensive remodeling of the left ventricle (LV) in young people with different baseline blood pressure (BP) level. Materials and methods. 981 people aged 20-29 years were examined. BP was measured before and during the stress. Transthoracic echocardiography was performed. Results. Hypertensive LV remodeling was detected in 199 (32.10%) persons. The pathological stress response of BP was observed in 66 (10.64%) subjects. The pathological stress response of BP was associated with hypertensive remodeling of the LV (OR 8.45, 95% CI 4.97-14.36). Conclusion: The pathological stress response of BP is a risk factor for the hypertensive LV remodeling in patients without hypertension by the office BP measurement.


About the authors

Elena Sklyannaya

Donetsk National Vedical University n.a. M. Gorky

Author for correspondence.
Email: elena_skl1979@mail.ru
ORCID iD: 0000-0002-0656-7097
SPIN-code: 5608-1287

Ukraine, 283003, Donetsk, Illicha av.

кандидат медицинских наук, доцент кафедры госпитальной терапии

References

  1. Зволинская Е.Ю., Александров А.А. Оценка риска развития сердечно-сосудистых заболеваний у лиц молодого возраста. Кардиология 2010; 8: 37-47.
  2. Лямина Н.П., Наливаева А.В., Сенчихин В.Н., Липчанская Т.П. Маскированная артериальная гипертензия у лиц молодого возраста: выявляемость, выраженность кардиоваскулярных факторов риска и прогноз с учетом гендерных различий. Российский кардиологический журнал 2017; 4 (144): 7-12.
  3. Aurigemma G.P., Gottdiener J.S., Shemanski L., Gardin J., Kitzman D. Predictive value of systolic and diastolic function for incident congestive heart failure in the elderly: the cardiovascular health study. J Am Coll Cardiol 2001; 37: 1042–1048.
  4. Bobrie G., Clerson P., Menard J., Postel-Vinay N., Chatellier G., Plouin P.F. Masked hypertension: a systematic review. J Hypertens 2008; 26: 1715–1725.
  5. Devereux R.B., Alonso D.R., Lutas E.M. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am. J. Cardiol 1986; 57: 450-458.
  6. Fagard R.H., Cornelissen V.A. Incidence of cardiovascular events in white-coat, masked and sustained hypertension vs. true normotension: a meta-analysis. J Hypertens 2007; 25: 2193–2198.
  7. Levy D., Salomon M., D’Agostino R.B., Belanger A.J., Kannel W.B. Prognostic implications of baseline electrocardiographic features and their serial changes in subjects with left ventricular hypertrophy. Circulation 1994; 90: 1786–1793.
  8. Light K.C., Girdler S.S., Sherwood A., Bragdon E.E., Brownley K.A., West S.G., Hinderliter A.L. High stress responsivity predicts later blood pressure only in combination with positive family history and high life stress. Hypertension 1999; 33: 1458-1464.
  9. Mancia G., Fagard R., Narkiewicz K., Redon J., Zanchetti A., Böhm M., Christiaens T., Cifkova R., De Backer G., Dominiczak A., Galderisi M., Grobbee D.E., Jaarsma T., Kirchhof P., Kjeldsen S.E., Laurent S., Manolis A.J., Nilsson P.M., Ruilope L.M., Schmieder R.E., Sirnes P.A., Sleight P., Viigimaa M., Waeber B., Zannad F. 2013 ESH/ESC Guidelines for the management of arterial hypertension. Journal of hypertension 2013; 31 (7): 1281-1372.
  10. Marwick T.H., Gillebert T.C., Aurigemma G., Chirinos J., Derumeaux G., Galderisi M., Gottdiener J., Haluska B., Ofili E., Segers P., Senior R., Tapp R.J., Zamorano J.L. Recommendations on the Use of Echocardiography in Adult Hypertension: A Report from the European Association of Cardiovascular Imaging (EACVI) and the American Society of Echocardiography (ASE). European Heart Journal – Cardiovascular Imaging 2015; 16: 577–605.
  11. Piepoli M.F., Hoes A.W., Agewall S., Albus C., Brotons C., Catapano A.L., Cooney M.T., Corrà U., Cosyns B., Deaton C., Graham I., Hall M.S., Hobbs F.D.R., Løchen M.L., Löllgen H., Marques-Vidal P., Perk J., Prescott E., Redon J., Richter D.J., Sattar N., Smulders Y., Tiberi M., van der Worp H.B., van Dis I., Verschuren W.M.M.G. 2016 European Guidelines on cardiovascular disease prevention in clinical practice. European Heart Journal 2016; 37: 2315–2381.
  12. Sega R., Trocino G., Lanzarotti A., Carugo S., Cesana G., Schiavina R., Valagussa F., Bombelli M., Giannattasio C., Zanchetti A., Mancia G. Alterations of cardiac structure in patients with isolated office, ambulatory, or home hypertension: Data from the general population (Pressione Arteriose Monitorate E Loro Associazioni [PAMELA] Study). Circulation 2001; 104: 1385–1392.
  13. Sundstrom J., Neovius M., Tynelius P., Rasmussen F. Association of blood pressure in late adolescence with subsequent mortality: cohort study of Swedish male conscripts. BMJ 2011; 342: d643.473.
  14. Tsioufis C., Kokkinos P., Macmanus C., Thomopoulos C., Faselis C., Doumas M., Stefanadis C., Papademetriou V. Left ventricular hypertrophy as a determinant of renal outcome in patients with high cardiovascular risk. J Hypertens 2010; 28: 2299–2308.

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