Reaction of peripheral circulation to apnoea in young women with idiopatic arterial hypotency

Summary. The aim of the study was to study the response of peripheral vascular hemodynamics to apnea in young women with idiopathic arterial hypotension. Material and methods. A comparative analysis of the results of ultrasound scanning of peripheral arteries and veins was carried out in a trial with apnea between 19 women with idiopathic arterial hypotension - SBP 98 (92-98) mmHg and 11 women with normal arterial pressure - SBP 124 (121-126) mmHg. The age of women in both groups was 18-25 years. Measurement of blood pressure, peripheral oxygen saturation. Angioscanning was performed lying down, at rest, before and after a 20 second respiratory arrest. We studied the diameter, velocity of blood flow in vertebral, humeral, radial and posterior tibial arteries, and veins. Results. Apnea in young women with hypotension causes an increase in the diameter of a larger number of arteries than in the control group. With hypotension, there was a decrease in the rate of blood flow in the arteries in the absence of dynamics of venous blood flow velocity. Conclusions. These changes in peripheral blood flow in arterial hypotension should be considered as a manifestation of disadaptation. Disadaptation is caused by excessive endothelium-dependent dilatation of resistive vessels and oppression of the vasotonic reaction. Disadaptation is associated with excessive production of endothelium nitric oxide.