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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">Perm Medical Journal</journal-id><journal-title-group><journal-title xml:lang="en">Perm Medical Journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Пермский медицинский журнал (сетевое издание "Perm medical journal")</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0136-1449</issn><issn publication-format="electronic">2687-1408</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">109372</article-id><article-id pub-id-type="doi">10.17816/pmj393102-113</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Preventive and social medicine</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Профилактическая и социальная медицина</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Effectiveness of antiepidemic events in tuberculosis in context of changing epidemic process trend</article-title><trans-title-group xml:lang="ru"><trans-title>Эффективность противоэпидемических мероприятий при туберкулезе в условиях изменения тренда эпидемического процесса</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3695-3834</contrib-id><name-alternatives><name xml:lang="en"><surname>Dorofeeva</surname><given-names>I. K.</given-names></name><name xml:lang="ru"><surname>Дорофеева</surname><given-names>И. К.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Candidate of Medical Sciences, Associate Professor, Department of Epidemiology</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, доцент кафедры эпидемиологии</p></bio><email>atlz3@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4410-1677</contrib-id><name-alternatives><name xml:lang="en"><surname>Logvin</surname><given-names>F. V.</given-names></name><name xml:lang="ru"><surname>Логвин</surname><given-names>Ф. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Candidate of Medical Sciences, Acting Head of Department of Epidemiology</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, и.о. заведующего кафедрой эпидемиологии</p></bio><email>atlz3@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3656-8143</contrib-id><name-alternatives><name xml:lang="en"><surname>Maksimova</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Максимова</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Candidate of Medical Sciences, Associate Professor, Department of Epidemiology</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, доцент кафедры эпидемиологии</p></bio><email>atlz3@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0246-1145</contrib-id><name-alternatives><name xml:lang="en"><surname>Chernigovets</surname><given-names>L. F.</given-names></name><name xml:lang="ru"><surname>Черниговец</surname><given-names>Л. Ф.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Candidate of Medical Sciences, Associate Professor, Department of Epidemiology</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, доцент кафедры эпидемиологии</p></bio><email>atlz3@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0441-9197</contrib-id><name-alternatives><name xml:lang="en"><surname>Tyutyunkova</surname><given-names>N. G.</given-names></name><name xml:lang="ru"><surname>Тютюнькова</surname><given-names>Н. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Candidate of Medical Sciences, Associate Professor, Department of Epidemiology</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, доцент кафедры эпидемиологии</p></bio><email>atlz3@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1840-9627</contrib-id><name-alternatives><name xml:lang="en"><surname>Batashev</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Баташев</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Candidate of Medical Sciences, Associate Professor, Department of Epidemiology</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, доцент кафедры эпидемиологии</p></bio><email>atlz3@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Chernaya</surname><given-names>A. S.</given-names></name><name xml:lang="ru"><surname>Черная</surname><given-names>А. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Assistant, Department of Epidemiology</p></bio><bio xml:lang="ru"><p>ассистент кафедры эпидемиологии</p></bio><email>atlz3@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Rostov State Medical University</institution></aff><aff><institution xml:lang="ru">Ростовский государственный медицинский университет</institution></aff></aff-alternatives><content-language>ru</content-language><pub-date date-type="pub" publication-format="electronic" iso-8601-date="2022-07-15"><day>15</day><month>07</month><year>2022</year></pub-date><pub-date date-type="collection"><year>2022</year></pub-date><volume>39</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>102</fpage><lpage>113</lpage><history><date date-type="received" iso-8601-date="2022-07-15"><day>15</day><month>07</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-07-15"><day>15</day><month>07</month><year>2022</year></date></history><pub-history><event event-type="received"><event-desc>Received:<date date-type="received" iso-8601-date="2022-07-15"><day>15</day><month>07</month><year>2022</year></date></event-desc></event><event event-type="accepted"><event-desc>Accepted:<date date-type="accepted" iso-8601-date="2022-07-15"><day>15</day><month>07</month><year>2022</year></date></event-desc></event><event event-type="pub"><event-desc>Published:<pub-date date-type="pub" publication-format="electronic" iso-8601-date="2022-07-15"><day>15</day><month>07</month><year>2022</year></pub-date></event-desc></event></pub-history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Dorofeeva I.K., Logvin F.V., Maksimova E.A., Chernigovets L.F., Tyutyunkova N.G., Batashev V.V., Chernaya A.S.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, Дорофеева И.К., Логвин Ф.В., Максимова Е.А., Черниговец Л.Ф., Тютюнькова Н.Г., Баташев В.В., Черная А.С.</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Dorofeeva I.K., Logvin F.V., Maksimova E.A., Chernigovets L.F., Tyutyunkova N.G., Batashev V.V., Chernaya A.S.</copyright-holder><copyright-holder xml:lang="ru">Дорофеева И.К., Логвин Ф.В., Максимова Е.А., Черниговец Л.Ф., Тютюнькова Н.Г., Баташев В.В., Черная А.С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://permmedjournal.ru/PMJ/article/view/109372">https://permmedjournal.ru/PMJ/article/view/109372</self-uri><abstract xml:lang="en"><p><bold>Objective. </bold>To study the features of the formation of the epidemic situation for tuberculosis and to evaluate the effectiveness of antiepidemic events in separate age groups.</p> <p><bold>Materials and methods. </bold>A retrospective analysis of the incidence of tuberculosis in Rostov-on-Don from 1992 to 2017 was conducted. The dynamics of the incidence of active tuberculosis, respiratory system tuberculosis and forms with bacillus discharge with the determination of the trend and its quantitative assessment was studied; the age structure of tuberculosis patients was analyzed depending on the direction and severity of the trend.</p> <p><bold>Results.</bold> The incidence of tuberculosis has been increasing in Rostov-on-Don since 1993, and from 2003 to 2008, the average long-term incidence of active tuberculosis, respiratory tuberculosis and forms with bacillus excretion was maximum. Since 2009, the direction of trends has changed, the period from 2009 to 2013 is characterized by a "pronounced" downward trend and since 2014, the incidence rates have been minimal. In the age structure of patients with active tuberculosis, the proportion of persons aged 40-49 is decreasing, and in 2014–2017, the proportion of persons aged 50–59 years is also falling. Since 2009, the proportion of persons aged 18–29 has increased, and in 2009–2013 the proportion of children has grown. In 2014–2017, the proportion of persons over 60 years of age increased among those who fell ill.</p> <p><bold>Conclusion.</bold> The most effective events are carried out in the group of 40–59 years, less effective – among children and persons aged 15–17 and 30–39 years. The results of the research will allow us to adjust preventive measures among children, teenagers and young people.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель.</bold> Изучение особенностей формирования эпидемической ситуации по туберкулезу и оценка эффективности проводимых противоэпидемических мероприятий в отдельных возрастных группах.</p> <p><bold>Материалы и методы.</bold> Проведен ретроспективный анализ заболеваемости туберкулезом в городе Ростове-на-Дону с 1992 по 2017 г. Изучалась динамика заболеваемости активным туберкулезом, туберкулезом органов дыхания и формами с бацилловыделением с определением тенденции и ее количественной оценкой, проанализирована возрастная структура заболевших туберкулезом в зависимости от направления и выраженности тенденции.</p> <p><bold>Результаты.</bold> В г. Ростове-на-Дону заболеваемость туберкулезом росла с 1993 г., с 2003 по 2008 г. среднемноголетние показатели заболеваемости активным туберкулезом, туберкулезом органов дыхания и формами с бацилловыделением максимальны. С 2009 г. меняется направление трендов, период с 2009 по 2013 г. характеризуется «выраженной» тенденцией к снижению, с 2014 г. показатели заболеваемости минимальны. В возрастной структуре заболевших активным туберкулезом снижается доля лиц в возрасте 40–49 лет, а в 2014–2017 гг. – уменьшается и доля лиц в возрасте 50–59 лет. С 2009 г. росла доля лиц в возрасте 18–29 лет, а в 2009–2013 гг. увеличилась доля детей. В 2014–2017 гг. среди заболевших увеличилась доля лиц старше 60 лет.</p> <p><bold>Выводы.</bold> Наиболее эффективны проводимые мероприятия в группе 40–59-летних, менее эффективны – среди детей и лиц в возрасте 15–17 и 30–39 лет. Результаты исследования позволят скорректировать профилактические мероприятия среди детей, подростков и лиц молодого возраста.</p></trans-abstract><kwd-group xml:lang="en"><kwd>tuberculosis</kwd><kwd>morbidity</kwd><kwd>trend</kwd><kwd>age structure</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>туберкулез</kwd><kwd>заболеваемость</kwd><kwd>тенденция</kwd><kwd>возрастная структура</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">The global plan to stop TB 2011-2015: transforming the fight towards elimination of tuberculosis. 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