Perm Medical JournalPerm Medical Journal0136-14492687-1408Eco-Vector12020310.17816/pmj39654-61Research ArticleEfficacy of enterosorption in treatment of Covid-19 in pregnant womenRomanovskayaA. V.<p>MD, PhD, Professor, Department of Obstetrics and Gynecology, Pediatric Faculty</p>annavictorovna@mail.ruMikhailovaE. V.<p>MD, PhD, Head of the Department of Pediatric Infectious Diseases and Polyclinic Pediatrics named after N.R. Ivanov</p>annavictorovna@mail.ruDenisyukN. E.<p>Assistant, Department of Obstetrics and Gynecology, Pediatric Faculty</p>annavictorovna@mail.ruTyapkinaD. A.<p>Student</p>annavictorovna@mail.ruV.I. Razumovsky Saratov State Medical University0601202339654610501202305012023Copyright © 2023, Eco-Vector2023<p><strong>Objective. </strong>To optimize the treatment of pregnant women with a moderate form of COVID-19 by including a sorbent in complex therapy.</p>
<p><strong>Materials and methods. </strong>Pregnant women (<em>n</em> = 87) with a gestational term of 30 weeks or more were divided into 2 groups. Group 1 (<em>n</em> = 42) received standard treatment for COVID-19. Group 2 (<em>n</em> = 45) received an additional preparation of colloidal silicon dioxide. The following endotoxemia indicators were assessed: concentrations of C-reactive protein (CRP), interleukin-6 (IL-6), medium mass molecules (MМM). The course of pregnancy and complications of childbirth were evaluated.</p>
<p><strong>Results. </strong>At the peak stage of the disease, in patients of group 2 the level of МММ was 0,43 opt. units lower, CRP 7.1 mg / l lower, IL-6 2.3 ng / ml lower than in women of group 1.</p>
<p>Anemia, fetal growth retardation, threatening preterm birth, fetoplacental insufficiency, polyhydramnios and oligohydramnios was diagnosed rarely in group 2; the average fetal weight was 256 g more, the average fetal height was 2.4 cm more than in group 1. In group 2, there were fewer children with moderate and severe asphyxia.</p>
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