Perm Medical JournalPerm Medical Journal0136-14492687-1408Eco-Vector4976210.17816/pmj37485-90Research ArticleInformative significance of morphological methods for diagnosis of tumor processesBulatovaI. A.<p>MD, PhD, Professor, Department of Faculty Therapy №2 of Professional Pathology and Clinical Laboratory Diagnostics</p>bula.1977@mail.ruPaduchevaS. V.<p>Candidate of Medical Sciences, Head of Clinical Diagnostic Laboratory</p>bula.1977@mail.ruE.A. Vagner Perm State Medical UniversityCity Clinical Hospital №2 named after F.Kh. Gral0611202037485900611202006112020Copyright © 2020, Bulatova I.A., Paducheva S.V.2020<p><strong>Objective.</strong> To assess the comparability of the cytological and histological studies of material of different localizations.</p>
<p><strong>Materials and methods.</strong> The work is based on the analysis of results of cytological and histological studies in 48 patients examined at Perm Regional Oncological Dispensary in 2019.</p>
<p><strong>Results.</strong> It was established that out of 22 mammary punctates, diagnosis of cancer was confirmed in 20 patients with coincidence validity criterion of 91 %. Out of 14 preparations of skin, 13 cases were histologically confirmed that constituted 92.8 %. When studying the lymph node punctate, one mismatch was detected. Out of 6 thyroid punctates, there were 5 confirmed ones. Percentage of false-positive cytological conclusions was on average 7 %, false-negative 1 %.</p>
<p><strong>Conclusions.</strong> Comparability of cytological and histological studies according to the results of data analysis ranged from 50 to 100 % depending on localization and was on average 91.6 %.</p>Cytological studyhistological studyЦитологическое исследованиегистологическое исследование[Malignant neoplasms in Russia in 2018 (morbidity and mortality). Edited by A.D. Kaprina, V.V. Starinskogo, G.V. Petrovoy. Moscow: MNIOI them. P.A. Herzen – branch of the National Medical Research Center of Radiology of the Ministry of Health of Russia 2019; 250 (in Russian).][Volchenko N.N., Polonskaya N.Yu. Cytological method in the diagnosis of tumors and tumor-like processes. Clinical Cytology News from Russia 2018; 22 (1–2): 23–29 (in Russian).][Kronz J.D., Westra W.H., Epstein J.I. Mandatory second opinion surgical pathology at a large referral hospital. Cancer 1999; 86 (11): 2426–2435.][Santoso J.T., Coleman R.L., Voet R.L. et al. Pathology slide review in gynecologic oncology. Obstet Gynecol 1998; 91: 730–734.][Selman A.E., Niemann T.H., Fowler J.M., Copeland LJ. Quality assurance of second opinion pathology in gynecologic oncology. Obstet Gynecol 1999; 94 (2): 302–306.][Chan Y.M., Cheung A.N., Cheng D.K. et al. Pathology slide review in gynecologic oncology: routine or selective? Gynecol Oncol 1999; 75: 267–271.][Hamady Z.Z., Mather N., Lansdown M.R. et al. Surgical pathological second opinion in thyroid malignancy: impact on patients’ management and prognosis. Eur J Surg Oncol 2005; 31 (1): 74–77.][Fedyanin M.Yu. A clinical oncologist's perspective. How will morphological examination of tumors of the colon and genitourinary system affect the tactics of treatment? Malignant tumors 2018; 8 (3s1): 96–104 (in Russian).]