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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Perm Medical Journal</journal-id><journal-title-group><journal-title xml:lang="en">Perm Medical Journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Пермский медицинский журнал (сетевое издание "Perm medical journal")</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0136-1449</issn><issn publication-format="electronic">2687-1408</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">6793</article-id><article-id pub-id-type="doi">10.17816/pmj34294-102</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">CARDIOVASCULAR AND INFLAMMATORY BOWEL DISEASES: COMORBIDITY OR POLYMORBIDITY?</article-title><trans-title-group xml:lang="ru"><trans-title>ЗАБОЛЕВАНИЯ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ И ВОСПАЛИТЕЛЬНЫЕ ЗАБОЛЕВАНИЯ КИШЕЧНИКА: КОМОРБИДНОСТЬ ИЛИ ПОЛИМОРБИДНОСТЬ?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Khlynova</surname><given-names>O V</given-names></name><name xml:lang="ru"><surname>Хлынова</surname><given-names>Ольга Витальевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., член-корр. РАН, профессор кафедры госпитальной терапии,</p></bio><email>olgakhlynova@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tuev</surname><given-names>A V</given-names></name><name xml:lang="ru"><surname>Туев</surname><given-names>Александр Васильевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, зав. каф. госпитальной терапии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vasilets</surname><given-names>L M</given-names></name><name xml:lang="ru"><surname>Василец</surname><given-names>Любовь Михайловна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор кафедры госпитальной терапии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kuznetsova</surname><given-names>E S</given-names></name><name xml:lang="ru"><surname>Кузнецова</surname><given-names>Екатерина Сергеевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>студентка 6 курса лечебного факультета</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">Пермский государственный медицинский университет им. академика Е.А. Вагнера</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2017</year></pub-date><volume>34</volume><issue>2</issue><issue-title xml:lang="en">VOL 34, NO2 (2017)</issue-title><issue-title xml:lang="ru">ТОМ 34, №2 (2017)</issue-title><fpage>94</fpage><lpage>102</lpage><history><date date-type="received" iso-8601-date="2017-07-11"><day>11</day><month>07</month><year>2017</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Khlynova O.V., Tuev A.V., Vasilets L.M., Kuznetsova E.S.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, Хлынова О.В., Туев А.В., Василец Л.М., Кузнецова Е.С.</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Khlynova O.V., Tuev A.V., Vasilets L.M., Kuznetsova E.S.</copyright-holder><copyright-holder xml:lang="ru">Хлынова О.В., Туев А.В., Василец Л.М., Кузнецова Е.С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://permmedjournal.ru/PMJ/article/view/6793">https://permmedjournal.ru/PMJ/article/view/6793</self-uri><abstract xml:lang="en"><p>The review of literature, devoted to the problem of associated course of cardiovascular diseases among patients with inflammatory bowel diseases (IBD) (Crohn’s disease and ulcerous colitis) is presented in the paper. The data on the prevalence, common etiological and pathogenetic factors, peculiarities of clinical picture in IBD patients, when associated with a number of cardiovascular diseases, were analyzed. The results of work aimed at characterization of peculiar features of patients’ genetic, immunological and hemostesiological profile with syntropia of these diseases are indicated.</p></abstract><trans-abstract xml:lang="ru"><p>Представлен обзор литературы, посвященный описанию вопроса о сочетанном течении заболеваний сердечно-сосудистой системы среди лиц с воспалительными заболеваниями кишечника (ВЗК) (болезнь Крона и язвенный колит). Проанализированы данные о распространенности, общности этиологических и патогенетических факторов, особенностях клинической картины у пациентов с ВЗК при их ассоциированном течении с рядом заболеваний сердечно-сосудистой системы. Приведены результаты работ по характеристике особенностей генетического, иммунологического и гемостезиологического профиля пациентов при синтропии заболеваний.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Cardiovascular pathology</kwd><kwd>inflammatory bowel diseases</kwd><kwd>Crohn’s disease</kwd><kwd>ulcerous colitis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Патология сердечно-сосудистой системы</kwd><kwd>воспалительные заболевания кишечника</kwd><kwd>болезнь Крона</kwd><kwd>язвенный колит</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Alkan E., Serkan M., Yıldırım B. Atherosclerosis in inflammatory bowel disease. Turk J Gastroenterol 2014; 25 (1): 20-25.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Bernstein С., Blanchard J., Houston D., Wanda A. The incidence of deep venous thrombosis and pulmonary embolism among patients with inflammatory bowel disease. 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