Perm Medical JournalPerm Medical JournalПермский медицинский журнал (сетевое издание "Perm medical journal")0136-14492687-1408Eco-Vector722910.17816/pmj346%pArticlesСтатьиTHE POSSIBILITY OF USING THE MELD SCALE FOR DETERMINING SEVERITY OF LIVER CIRRHOSISTHETHE POSSIBILITY OF USING THE MELD SCALE FOR DETERMINING SEVERITY OF LIVER CIRRHOSISBulatovaIrinaБулатоваИрина Анатольевнаbula.1977@mail.ruhttps://orcid.org/0000-0001-8255-088X2581-7279PaduchevaSvetlanaПадучеваСветлана Вячеславовна
Russian Federation

ассистент кафедры клиническая лабораторная диагнстика ФДПО

paducheva_sv@mail.ruhttps://elibrary.ru/author_profile.asp?id=953430ShchekotovaAlevtinaЩекотоваАлевтина Павловнаal_shchekotova@mail.ruShchekotovaIrinaЩекотоваИрина Владимировнаshchekotirina@mail.ruПермский государственный медицинский университет15122017346VOL 34, NO6 (2017)ТОМ 34, №6 (2017)02122017Copyright ©; 2018, Bulatova I., Paducheva S., Shchekotova A., Shchekotova I.Copyright ©; 2018, Булатова И.А., Падучева С.В., Щекотова А.П., Щекотова И.В.2018Bulatova I., Paducheva S., Shchekotova A., Shchekotova I.Булатова И.А., Падучева С.В., Щекотова А.П., Щекотова И.В.http://creativecommons.org/licenses/by-sa/4.0https://permmedjournal.ru/PMJ/article/view/7229

Objective: to Study the possibility of using the MELD scale to determine the severity of CKD and to determine its diagnostic capabilities.Methods:we Examined 30 patients with CKD, of which 15 patients were compensated stage of CKD (grade a+) Child-Pugh and 15 people with decompensated cirrhosis (class C). In the blood was evaluated the concentration of total bilirubin and creatinine were calculated INR and the MELD index.Results: the Calculated MELD index using the indicators of total bilirubin, creatinine and INR increased with the progression of CKD 5 in the stage of compensation to 26 in decompensated stage (p<0.001) and directly correlated with the severity of cirrhosis, assessed by Child-Pugh (rs=0,64; p=0.005). The threshold index value of MELD for the differentiation of compensated stage decompensated CPU from equal to 11.Conclusions:MELD Calculated index allows to differentiate the degree of severity of CKD with a sensitivity of 73.3% and a specificity of 84.6%. When the value of the index, MELD less than or equal to 11 are diagnosed with compensated stage of the CPU, a value of more than 11 sets of decompensated cirrhosis.Ваши исправления помогают повысить качество машинного переводаСообщить об ошибке

Objective: to Study the possibility of using the MELD scale to determine the severity of CKD and to determine its diagnostic capabilities.

Methods:we Examined 30 patients with CKD, of which 15 patients were compensated stage of CKD (grade a+) Child-Pugh and 15 people with decompensated cirrhosis (class C). In the blood was evaluated the concentration of total bilirubin and creatinine were calculated INR and the MELD index.

Results: the Calculated MELD index using the indicators of total bilirubin, creatinine and INR increased with the progression of CKD 5 in the stage of compensation to 26 in decompensated stage (p<0.001) and directly correlated with the severity of cirrhosis, assessed by Child-Pugh (rs=0,64; p=0.005). The threshold index value of MELD for the differentiation of compensated stage decompensated CPU from equal to 11.

Conclusions:MELD Calculated index allows to differentiate the degree of severity of CKD with a sensitivity of 73.3% and a specificity of 84.6%. When the value of the index, MELD less than or equal to 11 are diagnosed with compensated stage of the CPU, a value of more than 11 sets of decompensated cirrhosis.

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