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In these diseases, the immune system doesn’t work properly and releases inflammatory chemicals that attacks joint tissue. The resulting inflammation attacks Jointstissues and can cause joint swelling, increased joint fluid, cartilage and bone damage, and muscle loss. Nerves in the joints are activated, causing pain. The inflammatory chemicals may also directly activate the nerves of the body and lead to pain.

https://www.youtube.com/watch?v=_8_4p9f2qu8