Biological activity of chitosan nanoparticle dispersions produced by fractional precipitation
- Authors: Popova E.V.1, Domnina N.S.2, Novikova I.I.1, Kovalenko N.M.1, Krasnobaeva I.L.1, Zorin I.M.2
-
Affiliations:
- All-Russian Research Institute for Plant Protection
- St. Petersburg State University
- Issue: Vol 60, No 2 (2024)
- Pages: 177-182
- Section: Articles
- URL: https://permmedjournal.ru/0555-1099/article/view/674566
- DOI: https://doi.org/10.31857/S0555109924020073
- EDN: https://elibrary.ru/GAAFKU
- ID: 674566
Cite item
Abstract
An assessment was made of the antifungal and immunomodulatory activity of dispersions of chitosan nanoparticles obtained by fractional precipitation at pH 5.0 and pH 7.5 using chitosan of different molecular weights. The dispersion of nanoparticles obtained at pH 5 has increased fungistatic activity against C. sativus and A. solani, due to the higher availability of amino groups in looser nanoparticles. This dispersion showed immunostimulating activity, increasing the resistance of wheat to dark brown spot. It was also established that the elicitor activity of dispersions of chitosan nanoparticles is significantly higher than the activity of solutions of the original polymer.
Full Text

About the authors
E. V. Popova
All-Russian Research Institute for Plant Protection
Author for correspondence.
Email: elzavpopova@mail.ru
Russian Federation, 196608, St. Petersburg, Pushkin
N. S. Domnina
St. Petersburg State University
Email: elzavpopova@mail.ru
Russian Federation, 199034, St. Petersburg, Petergof
I. I. Novikova
All-Russian Research Institute for Plant Protection
Email: elzavpopova@mail.ru
Russian Federation, 196608, St. Petersburg, Pushkin
N. M. Kovalenko
All-Russian Research Institute for Plant Protection
Email: elzavpopova@mail.ru
Russian Federation, 196608, St. Petersburg, Pushkin
I. L. Krasnobaeva
All-Russian Research Institute for Plant Protection
Email: krasnobaeva08@mail.ru
Russian Federation, 196608, St. Petersburg, Pushkin
I. M. Zorin
St. Petersburg State University
Email: elzavpopova@mail.ru
Russian Federation, 199034, St. Petersburg, Petergof
References
- Варламов В. П., Ильина А. В., Шагдарова Б. Ц., Луньков А. П., Мысякина И. С. // Успехи биологической химии. 2020. Т. 60. С. 317–368.
- Wang W., Meng Q., Li Q., Liu J., Zhou M., Jin Z., Zhao K. // Int. J. Mol. Sci. 2020.V. 21. № 2. P. 487. https://doi.org/10.3390/ijms21020487
- Saharan V., Pal A. // Chitosan Based Nanomaterials in Plant Growth and Protection. Springer Briefs in Plant Science. Springer New Delhy, 2016. 55 р. https://doi.org/10.1007/978-81-322-3601-6
- Варламов В. П., Немцев С. В., Тихонов В. Е. Хитин и хитозан: природа, получение и применение. М.: Российское Хитиновое общество, 2010. 292 с.
- El Hadrami A., Adam L. R., El Hadrami I., Daayf F. // Marine Drugs. 2010. V. 8. № . 4. P. 968–987. https://doi.org/10.3390/md8040968
- Badawy M. E., Rabea E. I. // Int. J. Carbohydrate Chemistry. 2011. P. 1–29. https://doi.org/10.1155/2011/460381
- Тютерев С. Л. Природные и синтетические индукторы устойчивости растений к болезням. СПб: ВИЗР, 2014. 212 с.
- Kulikov S. N., Tikhonov V. E., Blagodatskikh I. V., Bezrodnykh E., Lopatin S., Khayrullin R. et al. // Carbohydrate Polymers 2012. V. 87. P. 545–550. https://doi.org/10.1016/j.carbpol.2011.08.017
- Mourya V. K., Inamdar N. N. // Reactive & Functional Polymers, 2008. V. 68. Р. 1013–1051.
- Ильина А.В. // Рыбпром: технологии и оборудование для переработки водных биоресурсов. 2010. № 2. С. 70–75.
- Choudhary М. К., Saharan V. // International Journal of Chemical Studies. 2017. V. 5. № 4. P. 1489–1494.
- Hendrickson C., Garett H., Bunderson L. // Agri Res. & Tech.: Open Access J. 2017. V. 11. № . 1. P. 555803. https://doi.org/10.19080/ARTOAJ.2017.11.555803
- Bandara S., Du H., Carson L., Bradford D. // Nanomaterials. 2020. V. 10. P. 1–32. https://doi.org/10.3390/nano10101903
- Kumaraswamy R. V., Kumari S., Choudhary R. C., Pal A., Raliya R., Biswas P., Saharan V. // Int. J. Boil. Macromol. 2018. V. 113. P. 494–506. https://doi.org/10.1007/978-3-030-12496-0_5
- Eshghi S., Hashemi M., Mohammadi A., Badii F., Mohammadhoseini Z., Ahmadi K. // Food Bioprocess Technol. 2014. V. 7. № 8. P. 2397–2409. https://doi.org/10.1007/s11947-014-1281-2
- Shukla S. K., Mishra A. K., Arotiba O. A., Mamba B. B. // Int. J. Biol. Macromol. 2013. V. 59. P. 46–58. https://doi.org/10.1016/j.ijbiomac.2013.04.043
- Khot L. R., Sankaran S., Maja J., Ehsani R. // Crop. Protection. 2012. V. 35. P. 64–70. https://doi.org/10.1016/j.cropro.2012.01.007
- Ing L. Y., Zin N. M., A., Katas H. // Int. J. Biomater. 2012. V. 1. P. 2–9. https://doi.org/10.1155/2012/632698
- Abdeltwab W. M., Abdelaliem Y. F., Metry W. A., Eldeghedy M. // J. Adv. Lab. Res. Biol. 2019. V. 10. P. 8–15.
- Oh J.-W., Chun S. C., Chandrasekaran M. // Agronomy. 2019. V. 9. P. 21. https://doi.org/10.3390/agronomy9010021
- Chandra S., Chakraborty N., Dasgupta A., Sarkar J., Panda K., Acharya K. // Sci. Rep. 2015. V. 5. P. 1–14. https://doi.org/10.1038/srep15195
- Sathiyabama M., Manikandan A. // Carbohydrate Polymers. 2016. V. 154. P. 241–246. https://doi.org/10.1016/j.carbpol.2016.06.089
- Siddaiah C. N., Satyanarayana N. R., Mudili V., Gupta V. K., Kalagatur N. K., Satyavati T. et al. // Sci. Rep. 2018. V. 8. № 1. P. 2485. https://doi.org/10.1038/s41598–017–19016-z
- Власов П. С., Киселев А. А., Домнина Н. С., Попова Э. В., Тютерев С. Л. // Журнал прикладной химии. 2009. № 9. C. 1571. https://doi.org/10.1134/S1070427209090298
- Popova E. V., Domnina N. S., Zorin I. M., Lezov A. A., Novikova I. I., Krasnobaeva I. L. // Nanobiotechnology Reports. 2023. V. 18. № 2. P. 238–246. https://doi.org/10.1134/s2635167623700088
- Методические рекомендации по испытанию химических веществ на фунгицидную активность / Под ред. Е. И. Андреева, В. С. Картомышева. М.: НИИТЭХИМ, 1990. 52 с.
- Rampino A., Borgogna M., Blasi P., Bellich B., Cesàro A. // Int. J. Pharm. 2013. V. 455. P. 219. https://doi.org/10.1016/j.ijpharm.2013.07.034
- Nugraheni P. S., Soeriyadi A. H., Ustadi U., Sediawan W. B., Budhijanto W. // J. Eng. Technol. Sci. 2019. V. 51. № 3. P. 430. https://doi.org/10.5614/j.eng.technol.sci.2019.51.3.9
- Попова Э. В., Зорин И. М., Домнина Н. С., Новикова И. И., Краснобаева И. Л. // Журнал общей химии. 2020. Т. 90. № 7. С. 1124–1132. https://doi.org/10.31857/s0044460x20070173
- Купреев Н. И. Кузнецов В. А. Способ получения наночастиц низкомолекулярного хитозана. Пат. № 2428432 (Рос-сия). 2011.
- Милушева Р. Ю., Рашидова С. Ш. // Высокомол. соед. Серия С. 2017. Т. 59. № 1. С. 33. https://doi.org/10.7868/S2308114717010058
- Ing L. Y., Zin N. M., Sarwar A., Katas H. // Int. J. Biomater. 2012. V. 1. P. 1–9. https://doi.org/10.1155/2012/632698
- Abdeltwab W. M., Abdelaliem Y. F., Metry W. A., Eldeghedy M. // J. Adv. Lab. Res. Biol. 2019. V. 10. № 1. P. 8–15.
Supplementary files
