Biological activity of chitosan nanoparticle dispersions produced by fractional precipitation

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Abstract

An assessment was made of the antifungal and immunomodulatory activity of dispersions of chitosan nanoparticles obtained by fractional precipitation at pH 5.0 and pH 7.5 using chitosan of different molecular weights. The dispersion of nanoparticles obtained at pH 5 has increased fungistatic activity against C. sativus and A. solani, due to the higher availability of amino groups in looser nanoparticles. This dispersion showed immunostimulating activity, increasing the resistance of wheat to dark brown spot. It was also established that the elicitor activity of dispersions of chitosan nanoparticles is significantly higher than the activity of solutions of the original polymer.

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About the authors

E. V. Popova

All-Russian Research Institute for Plant Protection

Author for correspondence.
Email: elzavpopova@mail.ru
Russian Federation, 196608, St. Petersburg, Pushkin

N. S. Domnina

St. Petersburg State University

Email: elzavpopova@mail.ru
Russian Federation, 199034, St. Petersburg, Petergof

I. I. Novikova

All-Russian Research Institute for Plant Protection

Email: elzavpopova@mail.ru
Russian Federation, 196608, St. Petersburg, Pushkin

N. M. Kovalenko

All-Russian Research Institute for Plant Protection

Email: elzavpopova@mail.ru
Russian Federation, 196608, St. Petersburg, Pushkin

I. L. Krasnobaeva

All-Russian Research Institute for Plant Protection

Email: krasnobaeva08@mail.ru
Russian Federation, 196608, St. Petersburg, Pushkin

I. M. Zorin

St. Petersburg State University

Email: elzavpopova@mail.ru
Russian Federation, 199034, St. Petersburg, Petergof

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