A Comprehensive Review on the State of the Art of Breast Cancers in Italy


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Breast cancer (BC) currently represents one of the most prevalent cancers among women worldwide and the leading cause of cancer death among women, also negatively affecting the quality of life (QoL) in patients. Over the past two decades, BC research has led to extraordinary advances in our understanding of the disease, resulting in more effective treatments. However, its occurrence is still increasing. Several new treatments are now under development worldwide, but they are not devoid of wellknown side effects, and a great number of patients develop endocrine resistance. Nevertheless, the design and synthesis of more suitable strategies and new drugs to treat breast cancers, overcome resistance and side effects, and obtain better therapeutic outcomes are needed. In this review, we summarize the therapies and the clinical studies currently ongoing in Italy for the treatment of BCs, mainly HER2+ MBC, HER2-low MBC, and TNBC, focusing on the most recent ones, also in consideration of diverse facets, including some aspects related to QoL. Finally, some studies related to the usefulness of physical activity in BC will be cited.

作者简介

Domenico Iacopetta

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria

Email: info@benthamscience.net

Jessica Ceramella

Department of Pharmacy, Health and Nutritional Sciences,, University of Calabria

Email: info@benthamscience.net

Alessia Catalano

Department of Pharmacy-Drug Sciences,, University of Bari "Aldo Moro"

编辑信件的主要联系方式.
Email: info@benthamscience.net

Camillo Rosano

U.O. Proteomica e Spettrometria di Massa,, IRCCS Ospedale Policlinico San Martino

Email: info@benthamscience.net

Annaluisa Mariconda

Department of Science, University of Basilicata

Email: info@benthamscience.net

Federica Giuzio

Department of Science, University of Basilicata

Email: info@benthamscience.net

Daniela Bonofiglio

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria

Email: info@benthamscience.net

Carmela Saturnino

Department of Science, University of Basilicata

Email: info@benthamscience.net

Pasquale Longo

Department of Chemistry and Biology, University of Salerno

Email: info@benthamscience.net

Maria Sinicropi

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria

Email: info@benthamscience.net

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