Nanomedicine: Innovative Strategies and Recent Advances in Targeted Cancer Therapy

  • Authors: Gautam R.1, Mittal P.2, Goyal R.3, Dua K.4, Mishra D.5, Sharma S.6, Singla R.1
  • Affiliations:
    1. Joint Laboratory of Artificial Intelligence for Critical Care Medicine, Department of Critical Care Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University
    2. Chitkara College of Pharmacy, Chitkara University
    3. Maharishi Markandeshwar (Deemed to be) University, M. M. College of Pharmacy
    4. Discipline of Pharmacy Graduate School of Health Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), University of Technology Sydney
    5. Department of Pharmaceutics, Indore Institute of Pharmacy
    6. Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM'S NMIMS, Shobhaben Pratapbhai Patel School of Pharmacy
  • Issue: Vol 31, No 28 (2024)
  • Pages: 4479-4494
  • Section: Anti-Infectives and Infectious Diseases
  • URL: https://permmedjournal.ru/0929-8673/article/view/645230
  • DOI: https://doi.org/10.2174/0109298673258987231004092334
  • ID: 645230

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Abstract

Nanomedicine's application of nanotechnology in medicine holds tremendous potential for diagnosing and treating life-threatening diseases such as cancer. Unlike conventional therapies, nanomedicine offers a promising strategy to enhance clinical outcomes while minimizing severe side effects. The principle of drug targeting enables specific delivery of therapeutic agents to their intended sites, making it a more precise and effective therapy. Combination strategies, such as the co-delivery of chemotherapeutic drugs with nucleic acids or receptor-specific molecules, are being employed to enhance therapeutic outcomes. Nanocarriers and drug delivery systems designed using these approaches offer resourceful co-delivery of therapeutic agents for anticancer therapy. Targeted drug delivery via nanotechnology-based techniques has become an urgent need and has shown significant improvements in therapeutic implications, pharmacokinetics, specificity, reduced toxicity, and biocompatibility. This review discusses the extrapolation of nanomaterials for developing innovative and novel drug delivery systems for effective anticancer therapy. Additionally, we explore the role of nanotechnology-based concepts in drug delivery research.

About the authors

Rupesh Gautam

Joint Laboratory of Artificial Intelligence for Critical Care Medicine, Department of Critical Care Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University

Author for correspondence.
Email: info@benthamscience.net

Pooja Mittal

Chitkara College of Pharmacy, Chitkara University

Email: info@benthamscience.net

Rajat Goyal

Maharishi Markandeshwar (Deemed to be) University, M. M. College of Pharmacy

Email: info@benthamscience.net

Kamal Dua

Discipline of Pharmacy Graduate School of Health Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), University of Technology Sydney

Email: info@benthamscience.net

Dinesh Mishra

Department of Pharmaceutics, Indore Institute of Pharmacy

Email: info@benthamscience.net

Sanjay Sharma

Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM'S NMIMS, Shobhaben Pratapbhai Patel School of Pharmacy

Email: info@benthamscience.net

Rajeev Singla

Joint Laboratory of Artificial Intelligence for Critical Care Medicine, Department of Critical Care Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University

Author for correspondence.
Email: info@benthamscience.net

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