PROGNOSTIC VALUE OF TRADITIONAL LABORATORY-INSTRUMENTAL INDICES IN CARDIOVASCULAR DISEASES

Abstract

Aim. To study and determine the prognostic value of screening indices and structure-functional status of myocardium in development of some cardiovascular diseases. Materials and methods. The study as well as correlation and regressive analysis of hemogram, coagulogram, lipidogram and echocardiogram indices was carried out in 249 patients with arterial hypertension (AH) and different forms of ischemic heart diseases IHD and 33 conditionally healthy persons. Results. Intergroup differences by eosinophil, basophile and lymphocyte content were established. The absolute values of LDLP and VLDLP CH grew depending on the severity of coronary pathology, but HDLP CH remained stably low. Hemostatic status was characterized by predominant activation of vasculothrombocyte component and fibrinolysis exhaustion. Unfavourable associations between atherogenic lipid fractions, coagulation component indices, peripheral blood cells and structural myocardial changes were established. Conclusion. The number of leukocytes, granulocytes and monocytes does not yield by its predicting CVD development ability to such traditional factors as sex, age, total cholesterol and fibrinogen level.

Full Text

ПРОГНОСТИЧЕСКИЕ ВОЗМОЖНОСТИ ТРАДИЦИОННЫХ лабораторно-инструментальнЫХ ПОКАЗАТЕЛЕЙ ПРИ сердечно-сосудистыХ заболеванияХ
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