MODERN APPROACH TO DIAGNOSIS AND TREATMENT OF PRIMARY HYPERPARATHYROIDISM

Aim. To determine the opportunities of subsequent use of a fine-needle aspiration puncture biopsy (FAPB) for assessment of intact parathyroid hormone (iPTH) level in the needle lavage (FAPB/PTH) and interstitial laser photocoagulation (ILPh) in treatment of primary hyperparathyroidism (PHPT). Materials and methods. 24 PHPT patients with thyroid changes US-visualized before the surgery were examined and operated. For the purpose of topic diagnosis, FAPB/PTH of the detected formations was performed. After belonging of these formations to thyroid changes was confirmed, patients underwent ILPh. Results. The conducted FAPB/PTH confirmed belonging of the visualized formations to thyroid changes. As a result of ILPh following FAPB/PTH, the changed thyroid regions were destroyed and the basic laboratory indices fell to the desired values. Thanks to subsequent use of FAPB/PTH and ILPh, the cause of PHPT including changes thyroid with elimination of its functional activity was liquidated in all patients. Conclusion. Subsequent use of FAPB/PTH and ILPh permits to liquidate PHPT cause with great accuracy, without anesthesia, without cosmetic defect in conditions of an out-patient department.

Hyperparathyroidism, puncture biopsy, low-invasive technique, interstitial laser photocoagulation, parathyroid hormone