Anxiety and depressive symptoms and level of Brain Derived Neurotrophic factor in patient with tension-type headache

Cover Page

Abstract


Purpose. Studying of correlation of Brain-Derived Neurotrophic Factor (BDNF) level in blood serum and expressiveness of anxiety and depressive symptoms in patients with tension-type headache.

Materials and methods. The research has included 82 patients with tension-type headache. For measurement of BDNF concentration in serum used a method of the enzyme immunodetection - the ELISA Kit test system.

Results. The BDNF level at patients with incidental infrequent and frequent TTH was comparable to group of control. The BDNF level at a chronic tension-type headache was decreased in comparison with the 1st, 2nd group and group of control The BDNF level changes depending on duration and intensity of tension-type headache. 

Conclusions. There is exhaustion not only the mediator, but also neurotrophic systems of a brain at a chronic tension-type headache. Measurement of BDNF concentration in serum will allow to estimate activity of cerebral neuroplasticity processes and to pick up neurotrophic therapy for faster start of serotonin system and knocking over of anxiety and depressive syndrome.


About the authors

Kseniia Tian

Тихоокеанский государственный медицинский университет

Author for correspondence.
Email: tyan_ksusha@mail.ru

Russian Federation, 690002, Россия, Владивосток, Острякова проспект 2

аспирант кафедры психиатрии и неврологии

Pavel Kalinsky

Тихоокеанский государственный медицинский университет

Email: kalinsky59@mail.ru

Russian Federation, 690002, Россия, Владивосток, Острякова проспект 2  

доктор медицинских наук, профессор кафедры психиатрии и неврологии

Anastasia Rakitova

Тихоокеанский государственный медицинский университет

Email: madwomanfox@mail.ru

Russian Federation, 690002, Россия, Владивосток, Острякова проспект 2

ассистент кафедры психиатрии и неврологии

References

Statistics

Views

Abstract - 178

Cited-By


PlumX


Copyright (c) 2018 Tian K., Kalinsky P., Rakitova A.

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies