Email this article BRAIN MAGNETORESONANCE MORPHOMETRY IN PATIENTS WITH POSTINSULT COGNITIVE DISORDERS
- Authors: Kulesh AA1, Drobakha VE1, Shestakov VV1
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- Issue: Vol 31, No 3 (2014)
- Pages: 39-45
- Section: Articles
- URL: https://permmedjournal.ru/PMJ/article/view/3350
- DOI: https://doi.org/10.17816/pmj31339-45
- ID: 3350
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Abstract
Aim. To assess the correlation between some indices of brain magnetoresonance morphometry, neurological, cognitive status and sleep quality in patients with ischemic stroke. Materials and methods. 29 patients aged 48-76 (10 men and 19 women) were examined in the acute period of stroke. Neuropsychological examination included Mini-mental State Examination (MMSE), Frontal Assessment Battery (FAB), Montreal Cognitive Assessment (MoCA), Watch Drawing Test (WDT), Words Test (5) (WT5), Schulte Table (ST) and Categoric Verbal Fluency Test (VF); sleep quality was assessed using Pittsburg Sleep Quality Index (PSQI). Margetoresonance (MR) tomography of the brain was performed; the following MR-morphometric indices were studied: brain volume ( V b), brain ventricular volume ( V v), brain volume to ventricular volume ratio (V b/ V v), leukoareosis square ( S l), infarction focus square ( S f), and hippocampus volume ( V h). Results. The results of correlation analysis of MR-morphometric indices, cognitive tests and sleep quality were received; the role of each index was estimated, morphometric differences between patients with disregulatory, disregulatory-dismnestic and dismnestic variant of cognitive disorders were studied. Conclusions. V v and V b/ V v are connected with global cognitive status and state of most cognitive spheres. Patients with disregulatory type of the postinsult cognitive disorders are characterized by the highest V v unlike patients with dismnestic variant. V f is connected with cognitive activity status as a whole, its executive component and sleep quality. V h is not associated with memory indices, but is associated with global cognitive status and regulatory-dynamic domen state. It is worthwhile to develop a complex of MR-morphometric indices which could have serve as an instrument for differential diagnosis of the postinsult cognitive disorders.
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