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Aim. To assess the correlation between some indices of brain magnetoresonance morphometry, neurological, cognitive status and sleep quality in patients with ischemic stroke. Materials and methods. 29 patients aged 48-76 (10 men and 19 women) were examined in the acute period of stroke. Neuropsychological examination included Mini-mental State Examination (MMSE), Frontal Assessment Battery (FAB), Montreal Cognitive Assessment (MoCA), Watch Drawing Test (WDT), Words Test (5) (WT5), Schulte Table (ST) and Categoric Verbal Fluency Test (VF); sleep quality was assessed using Pittsburg Sleep Quality Index (PSQI). Margetoresonance (MR) tomography of the brain was performed; the following MR-morphometric indices were studied: brain volume ( V b), brain ventricular volume ( V v), brain volume to ventricular volume ratio (V b/ V v), leukoareosis square ( S l), infarction focus square ( S f), and hippocampus volume ( V h). Results. The results of correlation analysis of MR-morphometric indices, cognitive tests and sleep quality were received; the role of each index was estimated, morphometric differences between patients with disregulatory, disregulatory-dismnestic and dismnestic variant of cognitive disorders were studied. Conclusions. V v and V b/ V v are connected with global cognitive status and state of most cognitive spheres. Patients with disregulatory type of the postinsult cognitive disorders are characterized by the highest V v unlike patients with dismnestic variant. V f is connected with cognitive activity status as a whole, its executive component and sleep quality. V h is not associated with memory indices, but is associated with global cognitive status and regulatory-dynamic domen state. It is worthwhile to develop a complex of MR-morphometric indices which could have serve as an instrument for differential diagnosis of the postinsult cognitive disorders.


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Copyright (c) 2014 Kulesh A.A., Drobakha V.E., Shestakov V.V.

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