Perspective directions of work on development of new types of biopathogens are presented in the paper. Convention on prohibition of biological weapon does not prevent development of new biopathogens. Success in gene engineering and molecular biology opens huge opportunities for receiving new biological agents and modification of the known ones. The basic directions in development of new types of biopathogens are the following: modification of especially dangerous infectious agents; modification of slow infectious agents; modification of uncontrolled infectious agents; synthesis of regulatory genes on the basis of viral vectors; modification of latent viruses; modification of oncogenes and oncogenic viruses; development of movable genetic elements based on phages, plasmids et c; synthesis of genes coding immunoprivileged organ and tissue proteins; modification of animal and plant toxins with elevated resistance to environmental factors; synthesis of genes coding formation of chemical and low concentration biological compounds with toxic or other regulatory effect. Development of new biopathogens will be accompanied by working out new methods for delivering such agents to the target. It is possible to develop a weapon possessing a high degree of selectivity and damaging genome of organism-target of a certain race, ethnos, nation.


  1. Маркович И. В. Биологическое оружие. Проблемы распространения, терроризма, политика противодействия. М.: Издательство ЛКИ 2011; 240.
  2. Cramplon J. Model system to evaluate the use of transgenic haematophagous incects to deliver protective vaccines. Parassitologm 2003; 41: 473-477.
  3. Dando M. Discriminating Bio-Weapons Could Target Ethnic Group. International Defense Review 1997; 30: 3.
  4. Dando M. Emerging Technologies: Biological Engineering and Biological Weapons A report by the Sunshine Project and TWN. 2004.
  5. Fraser C. Genomics and future biological weapons: the need for the preventive action by the biomedical community. Nature Genomics 2001; 29: 253-256.
  6. Gandioso J. Biological WMD The Threat From State. Sandia National Laboratories. Albuquerque NM USA; 2007; 247-249.
  7. Hu W. Design of retro viral vectors and helper cells for gene therapy. Parmacol Rev. 2000; 52: 493-511.
  8. Petro J. Biotechnology: impact on biological warfare and biodefense. Biosecurity and Bioterrorism: Biodefense Strategy, Practice and Science 2003; 1: 3.
  9. Piller C. Biological Weapons boost? Trends Biotechnol 2001; 3: 191.
  10. Piller C. Gene Wars: military control over the new Genetic Technologies. N. Y.: Beech Tree Books 1988; 243.
  11. Piller C. The Role of Biotechnology in Countering BTW Agent. Kluwer Academic Publisher 2001; 104.
  12. Uherek C. DNA-carrier proteins for target gene delivery. Аdvanced Drug Dilev 2000; 44: 2-3.
  13. Wheelis M. New technology and future developments in biological warfare. Disarmament Forum 2000; 4.



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