Email this article CLINICOROENTGENOLOGICAL AND MORPHOLOGICAL ASPECTS OF INTERSTITIAL LUNG DISEASES
- Authors: Frolova TI1, Terman EA1
-
Affiliations:
- Issue: Vol 30, No 1 (2013)
- Pages: 26-33
- Section: Articles
- URL: https://permmedjournal.ru/PMJ/article/view/3383
- DOI: https://doi.org/10.17816/pmj30126-33
- ID: 3383
Cite item
Full Text
Abstract
Aim. To assess the clinicoroentgenological and morphological signs of fibrosing processes in the lungs in primary diagnosis of different IIP forms, as independent pulmonary intersticial diseases. Materials and methods. One hundred and thirty nine patients observed after complex examination including pathomorphological verification were diagnosed idiopathic fibrosing alveolitis (IFA). Results. Additional profound pathomorphological investigation had the following results: usual interstitial pneumonia (UIP) as IFP basis, acute interstitial pneumonia (Hamman-Rich) and nonspecific interstitial pneumonia (NSIP). It was established that peculiarities of these IIP variants were revealed both in the early and late period of disease. Simultaneously, available inflammatory pulmonary reaction with marked sclerosis, even at the late stage of disease, proves alveolitis activity. Conclusion. Essential differences, absent in clinicoroentgenological manifestations of exacerbation of pulmonary process in chronic IIP permit to consider pathomorphological method to be the main method of nosologic ILD diagnosis.
Full Text
КЛИНИКО-РЕНТГЕНОЛОГИЧЕСКИЕ И ПАТОМОРФОЛОГИЧЕСКИЕ АСПЕКТЫ ИНТЕРСТИЦИАЛЬНЫХ ЗАБОЛЕВАНИЙ ЛЁГКИХ×
References
- Болевич С. Б., Коган Е. А., Козловская Л. В., Корнев Б. М., Осипенко В. И., Попова Е. Н., Фомин В. В. Идиопатический фиброзирующий альвеолит и идиопатические интерстициальные пневмонии. Интерстициальные болезни лёгких. М.: Литтерра 2007; 20–120.
- Илькович М. М., Новикова Л. Н., Двораковская И. В., Лучкевич В. С. Идиопатический фиброзирующий альвеолит. Диссеминированные заболевания лёгких. М.: ГЭОТАР-Медицина 2011; 24–84.
- Коган Е. А. Курс лекций по патологической анатомии / под ред. М. А. Пальцева. М.: Русский врач 2003; 260–291.
- Мухин Н. А. Интерстициальные болезни лёгких. М.: Литтерра 2007; 416.
- Чучалин А. Г., Котляров П. М., Георгиади С. Г. Рентгенография и компьютерная томография в диагностике различных видов идиопатических интерстициальных пневмоний. Пульмонология 2003; 13 (1): 90–95.
- Шмелёв Е. И. Дифференциальная диагностика интерстициальных болезней лёгких. Consilium medicum 2003; 5 (4): 176–181.
- Harbour R., Miller G. A new system for grading recommendations in evidence based guidelines. Br. Med. G. 2001; 323: 334–336.
- Guyatt G., Vist G., Falck-Ytter Y. An emerging consensus on grading recommendations. ACP G. Club 2006; 144: A8–A9.
- Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement/ ATS and ERS. Am. G. Respir. Crit. Care Med. 2000; 16: 646–664.
- Katzenstein A., Myers G. Idiopathic pulmonary fibrosis: clinical relevance of pathologic classification. Am. G. Respir. Crit. Care Med. 1998; 157: 1301–1315.
- Libow A. A. Definition and classification of interstial pneumonias in human pathology. Prog. Respir. Res 1975; 8: 1–33.
- Lynch G. P. Corticosteroids in idiopathic pulmonary fibrosis. Curr. Opin. Pulm. Med. 2001; Sep 7 (5): 298–308.
- Wells A. U. Histopathologic diagnosis in diffuse lung disease: an ailinggold standard. Am. G. Respir. Crit. Care Med. 2004; 170: 828–829.
Supplementary files
